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Index > Protein center > SOSTDC1(Gene name) > Human
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  • SOSTDC1 (Gene name),
  • Sclerostin domain-containing protein 1 (Protein name ),  SOSD1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    SOSTDC1(CDA019;USAG1);
    Protein name:
    Sclerostin domain-containing protein 1;
    Alternative:
    Uterine sensitization-associated gene 1 protein(USAG-1);Ectodermal BMP inhibitor(Ectodin);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with BMP2, BMP4, BMP6 and BMP7 with high affinity.
    Function:
    May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    206
    Sequence:
    50:
    MLPPAIHFYL | LPLACILMKS | CLAFKNDATE | ILYSHVVKPV | PAHPSSNSTL | 
    100:
    NQARNGGRHF | SNTGLDRNTR | VQVGCRELRS | TKYISDGQCT | SISPLKELVC | 
    150:
    AGECLPLPVL | PNWIGGGYGT | KYWSRRSSQE | WRCVNDKTRT | QRIQLQCQDG | 
    200:
    STRTYKITVV | TACKCKRYTR | QHNESSHNFE | SMSPAKPVQH | HRERKRASKS | 
    206:
    SKHSMS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Sclerostin domain-containing protein 1
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    E0465m
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    ELISA Kit for Human Sclerostin domain-containing protein 1
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    E0465h
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    ELISA Kit for Human Sclerostin domain-containing protein 1
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    E0465c
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    96T
    ELISA Kit for Human Sclerostin domain-containing protein 1
    Cat.:
    E0465r
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    Packing:
    96T
    CLIA Kit for Human Sclerostin domain-containing protein 1
    Cat.:
    U0465h
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    MSDS:
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    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Sclerostin domain-containing protein 1
    Cat.:
    U0465m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Sclerostin domain-containing protein 1
    Cat.:
    U0465r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Sclerostin domain-containing protein 1
    Cat.:
    U0465c
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Sclerostin domain-containing protein 1
    Cat.:
    P0465Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Sclerostin domain-containing protein 1
    Cat.:
    P0465Rb-m
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    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Sclerostin domain-containing protein 1
    Polyclonal Antibody for Human Sclerostin domain-containing protein 1
    Cat.:
    P0465Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Sclerostin domain-containing protein 1
    Monoclonal Antibody for Human Sclerostin domain-containing protein 1
    Monoclonal Antibody for Human Sclerostin domain-containing protein 1
    Monoclonal Antibody for Human Sclerostin domain-containing protein 1
    Protein for Human Sclerostin domain-containing protein 1
    Protein for Human Sclerostin domain-containing protein 1
    Protein for Human Sclerostin domain-containing protein 1
    Protein for Human Sclerostin domain-containing protein 1

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    References
    1. 1.
      "Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot."
      Laurikkala J. , Kassai Y. , Pakkasjaervi L. , Thesleff I. , Itoh N.
      Dev. Biol.264:91-105(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "A novel gene expressed in human pheochromocytoma."
      Liu F. , Xu X.R. , Qian B.Z. , Xiao H. , Chen Z. , Han Z.
      Submitted (2001-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Pheochromocytoma.
    3. 3.
      "A novel secreted WNT agonist is a requirement for epithelial-mesenchymal interactions."
      O'Shaughnessy R.F.L. , Yeo W. , Gautier J. , Jahoda C.A.B. , Christiano A.M.
      Submitted (2003-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Testis.
    5. 5.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Bone marrow.
    7. 7.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-38
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 74-206 (ISOFORM 1)
      tissue: Brain.
    9. 9.
      "USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney."
      Yanagita M. , Oka M. , Watabe T. , Iguchi H. , Niida A. , Takahashi S. , Akiyama T. , Miyazono K. , Yanagisawa M. , Sakurai T.
      Biochem. Biophys. Res. Commun.316:490-500(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH BMP2; BMP4 AND BMP7;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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